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Glutamine-blocking drug slows tumor growth and strengthens anti-tumor response
The drug, a "prodrug" version of the glutamine antagonist DON, was designed so that the active form of the drug is functional within the tumor. In theory, this compound could be used across a wide spectrum of cancer types, says Jonathan Powell, M.D., Ph.D., associate director of the Bloomberg~Ki…
Gastrointestinal complaints in children could signal future mental health problem: Adversity-induced disruptions in the body's gut microbes influence are linked to changes in brain function
"One common reason children show up at doctors' offices is intestinal complaints," said Nim Tottenham, a professor of psychology at Columbia and senior author on the study. "Our findings indicate that gastrointestinal symptoms in young children could be a red flag to primary care physicians for …
Vitamin D helps treat lethal drug-resistant TB
"Our study raises the possibility that vitamin D -- which is very safe and inexpensive -- could benefit this hard-to-treat group of patients by taking a novel approach to their treatment. By adding vitamin D to antibiotic treatment, we can boost the immune system to help the body to clear TB bug…